J-147
J-147 enhances mitochondrial function and is very effective in preventing oxidative stress. For example, J147 increases mitochondrial function by improving ATP levels (inhibiting ATP synthase, specifically ATP5A .
Fruit flies that were given J147 had a longer lifespan (9.5-12.8%) due to the effects on mitochondria. J147 can also reduce aging of the brain from use of γ-glutamyl amino acids and BCAAs .
In animal models, J147 has shown to decrease blood Glucose and HbA1c levels by increasing AMPK .
J147 reverses cognitive impairment in a mouse model of Alzheimer’s Disease (AD), and can improve Amyloid-Beta (Aβ) metabolism and reduce levels in the brain by reducing protein levels of β-Secretase (BACE) .
In animal models of AD, J147 can protect BBB permeability homeostasis and improve vascular function in the brain .
J147 grows the brain by increasing levels of both Nerve Growth Factor (NGF) and Brain-Derived Neurotrophic Factor (BDNF) .
CAS Number: 1807913-16-1 
1146963-51-0 (non-specific stereochemistry)
Molar mass: 350.341 g·mol−1
Formula: C18H17F3N2O2
Purity: ≥98%
| J-147 Basic information |
| Product Name: | J-147 |
| Synonyms: | J-147 |
| CAS: | 6-39 |
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